In heterogeneous network, femtocell is deployed inside macrocell coverage. Femtocell and macrocell use the same frequency as the resource. Thus, if the resources are not properly allocated, the interference will arise. The higher level of interference results in decreasing signal quality. Therefore, interference management is needed to increase network capacity and system performance. This research implements particle swarm optimization (PSO) algorithm to minimize interference on the heterogeneous network. Based on the simulation results, it is shown that PSO algorithm works efficiently to increase the throughput value of femto user equipment (femto UE) up to 62,2 Mbps by minimizing the interference.